The Technology
Many therapeutic drugs and nutraceutical ingredients exhibit poor water solubility, limiting their stability, bioavailability, and ultimately their therapeutic or nutritional effectiveness. Improving the formulation of these hydrophobic compounds remains a major challenge across the pharmaceutical, dietary supplement, and consumer health industries.
This technology introduces a novel class of indolium-based oligomers that spontaneously self-assemble into nanoparticles capable of encapsulating and stabilizing hydrophobic molecules in aqueous formulations. Unlike conventional surfactants or polymeric carriers, these oligomers are formed through a simple synthesis process and can incorporate a broad range of hydrophobic compounds, including pharmaceutical drugs and dietary supplements.
The resulting nanoparticles improve dispersion of poorly soluble compounds while offering formulation flexibility across multiple routes of administration, including oral, injectable, topical, and inhaled products. The platform is also compatible with a diverse range of active molecules, from small-molecule therapeutics to natural bioactive compounds, creating opportunities across both pharmaceutical and consumer health markets.
Advantages
- Novel nanoparticle platform for poorly water-soluble compounds
- Improves aqueous dispersion and formulation stability
- Simple and scalable preparation process
- Adaptable to multiple administration routes
- Applicable across pharmaceutical, dietary supplement, and consumer health products
Applications and Opportunities
- Delivery of hydrophobic pharmaceuticals
- Formulation of dietary supplements and natural bioactives
- Nutraceutical and functional food ingredients
- Reformulation and lifecycle management of existing products
Business Development Contacts
