Biocompatible adhesive microneedle for tissue repair and sealing

Researcher:
Prof. Boaz Mizrahi | Biotechnology and Food Engineering

Categories:

Medical Devices

 

The Technology

Adhesion of soft tissues, as well as their sealing, are of great significance in the clinical and Medical fields. Closing wounds with tissue adhesives presents challenges, as well as a significant opportunity to revolutionize bleeding control and to heal. Although various formulations have been developed for soft-tissue adhesives, tradeoffs between adhesive properties and tissue toxicity limit their clinical use. This technology uses innovative approach to developing a strong bio-adhesive microneedle (MN’s) composed of bio-adhesive methodologies combined with interlocking and swelling approaches. The sharp needle structure enables the microneedle patch to strongly fix onto various tissues via physical interlocking while the crosslinked bio-adhesive composition firmly anchors to cell membrane, allowing hemostasis and promote healing. The introduction of novel, reliable, cheap and safe surgical sealants and adhesives, which does not require trained medical staff for administration is expected to create lucrative opportunities for the market. Sealant from Microneedle patch using bio adhesive polymers will rely on the microneedle ability to mechanically penetrate the tissue without damaging it. In addition, the ability of mucoadhesive materials which are also capable of swelling in an aqueous medium, will further contribute to adhesion of the tissue by adding mechanical and chemical interlocking with the tissue.

Advantages

  • No pain
  • Dissolve microneedle
  • Carrier for drug delivery for superficial penetration

Applications and Opportunities

  • Wound healing
  •  Dermatology
  •  Cosmetics
  • Drug delivery
arrow Business Development Contacts
Motti Koren
Director of Business Development, Life Sciences