Research Area / Fields

  1. Molecular mechanisms of myofibril destruction to treat atrophy induced by aging, inactivity or disease.
  2. Molecular mechanisms of desmin intermediate filaments depolymerization to prevent muscle wasting.
  3. Regulation of muscle sensitivity to insulin to improve glycemic control in aging or disease.
  4. Maintenance of normal muscle mass in aging by tailormade diet regimes.

Short Bio

Shenhav Shemer is a leading expert in the field of muscle atrophy, and the molecular mechanisms underlying myofibril loss and muscle wasting in disease. Her lab masters two areas in cell biology, the biochemistry of the ubiquitin-proteasome system (UPS) and muscle biology/physiology. Research in her laboratory, at the faculty of biology at Technion Israel, brought major breakthroughs and new concepts into the UPS and muscle fields by uncovering the cellular and catabolic biochemical events leading to muscle wasting. The group has developed tools to study in vivo the molecular mechanisms underlying the loss of specific subunits from the myofibril and presented the first models for myofibril disassembly during atrophy as an ordered process.

Available Technologies for commercialization

arrow Business Development Contacts
Motti Koren
Director of Business Development, Life Sciences