A bioink formulation for 3D printing of skeletal muscle

Researcher:
Prof. Dror Seliktar | Biomedical Engineering

Categories:

Chemistry and Materials | Medical Devices

The Technology

Over the past century, revolutionary techniques were developed allowing organ and tissue transplantation from human donors. Although such therapies have been extremely valuable and lifesaving, they are far from being sustainable on a global scale. Despite these shortcomings, allogeneic transplantations are still the most viable therapeutic treatment option for some of the most serious forms of tissue and organ malfunction.
The technology demonstrate a new strategy for the fabrication of artificial skeletal muscle tissue with functional morphologies based on an innovative 3D bio-printing approach. This 3D bio-printing technique provide a novel approach that allows the design and construction of cellularized myo-structures of desired shape and size, hence representing a powerful biotechnological tool for regenerative muscle therapeutics. When combined with an appropriate biomimetic matrix and stem cell population, this strategy will pave the way for clinical testing of muscle implants with physiological muscle architecture and functionality.

Advantages

  • The 3D-printed material have been proven to contribute to regeneration of skeletal muscle
  • The technology provides a structural directionality required for the repair of functional striated muscle fibers
  • The mechanical properties are matched for the requirements of myogenesis.

Applications and Opportunities

  • Platform for artificial muscle implants and muscle regeneration
  • Soft tissue repair

 

arrow Business Development Contacts
Motti Koren
Director of Business Development, Life Sciences