The Technology
Limited bioavailability remains a critical challenge in effectively delivering lipophilic active pharmaceutical ingredients (APIs), nutraceuticals, and food additives. Our novel technology addresses this challenge by utilizing pheophytin—a chlorophyll-derived compound—as a natural bioenhancer extracted from agricultural residues. Pheophytin significantly increases the aqueous dispersibility and bioavailability of lipophilic molecules, demonstrated through substantial improvements in cannabidiol (CBD) absorption in preclinical studies. The innovation provides a versatile and sustainable solution, leveraging natural sources and advanced extraction methods to produce a highly effective bioavailability enhancer.
Preclinical studies confirmed that the presence of pheophytin substantially improved the solubility, stability, and systemic absorption of CBD, resulting in superior therapeutic efficacy. The technology has potential applications across a wide range of lipophilic compounds, from cannabinoids to nutraceuticals and food ingredients, significantly broadening its market relevance.
Advantages
- Significantly enhances bioavailability of lipophilic molecules.
- Derived from natural, sustainable agricultural residues.
- Demonstrated effectiveness in preclinical models.
- Enables lower therapeutic doses, reducing costs and potential side effects.
- Versatile application potential across multiple nutraceutical, pharmaceutical, and food markets.
Applications and Opportunities
- Enhancement of bioavailability for cannabinoids and other lipophilic nutraceuticals.
- Pharmaceutical applications, particularly for poorly soluble APIs.
- Food industry applications to improve the absorption and nutritional value of lipophilic vitamins, supplements, and functional food ingredients.
- Potential integration into nutraceutical, herbal, and functional food product markets, enhancing therapeutic outcomes and nutritional benefits.
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