The Technology
This technology introduces a non-invasive deep-tissue imaging system that uses millimeter-wave (mmWave) radar to detect and track gold nanoparticles (GNPs) in biological tissues. The system transmits low-power, non-ionizing radar signals and analyzes their reflections to localize and monitor the spatial distribution of GNPs inside the body. These FDA-approved nanoparticles are known for accumulating in tumor sites and crossing the blood-brain barrier, making them ideal for diagnostic and therapeutic tracking.
Using frequency-modulated continuous wave (FMCW) radar and a custom signal-processing algorithm, the system generates range-angle maps that precisely identify GNP location and concentration. This allows the system to perform non-contact imaging through barriers such as the skull or soft tissue, enabling 2D or 3D visualization of GNPs used in drug delivery systems or as standalone diagnostic markers.
Advantages
- Non-ionizing, safe alternative to CT/MRI
- Real-time imaging through biological barriers
- Detects both presence and concentration of GNPs
- Compact, low-cost, radar-based setup
- Allowing simultaneous monitoring of multiple individuals
- Enables monitoring over time
Applications and Opportunities
- Tissue imaging and tumor localization
- Tracking nanoparticle-based drug delivery
- Imaging for photothermal or photodynamic therapies
- Companion diagnostics in cancer and additional diseases
- Monitoring how GNPs accumulate, move, or clear from tissues
