Electrospun-coated medical devices

Prof. Eyal Zussman | Mechanical Engineering


Medical Devices

The Technology

Intubation-related morbidity is a well-known complication that usually involves the larynx and trachea. These problems are secondary to airway mucosal damage due to the presence of an endotracheal tube (ETT) which creates local pressure and pressure-like ulcer. The common clinical approach to airway mucosal damage is using systemic steroids hours to days prior to extubating.

The present technology consists of drug-eluting endotracheal tube for the local controlled drug release, which may be a steroid, for the treatment of endotracheal tube complications, by releasing the drug from the reservoir into the larynx and trachea in a controlled manner.

This ETT composed of endotracheal tube coated by biodegradable and/or pressure-responsive polymeric electrospun fibers, which loaded with at least one drug.

This coating technique could be utilized in other fields such as catheters, implants and other.


  • Local drug release
  • Prophylactic

Applications and Opportunities

  • Endotracheal tubes
  • Catheters
  • Implants
arrow Business Development Contacts
Dr. Gal Gur
Director of Business Development, Life Sciences