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Category: Pharmaceuticals and Biotechnology - OLD

A new sema3A derivative as a beneficial therapeutic strategy for immune mediated

Researcher: Zehava Vadasz |Prof. Emeritus Gera Neufeld

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Current therapies for systemic lupus erythematosus (SLE), asthma and IBD are only partially effective and more effective therapies are needed, especially in those patients with severe/highly active diseases. Semaphorin3A (sema3A) is well known for its regulatory functions at all stages...
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Categories: Pharmaceuticals and Biotechnology - OLD

Biocompatible quantum dots for neuronal stimulation and regeneration

Researcher: Prof. Avi Schroeder

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Neuronal injuries, including traumatic nerve damage and spinal cord injuries, severely impair sensory and motor functions, necessitating precise neuronal regeneration and axonal growth for effective recovery. Current treatments using electrical stimulation with invasive electrodes are limited by their lack of...
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Categories: Food and Agriculture - OLD|Pharmaceuticals and Biotechnology - OLD

Developing novel therapy for Duchenne Muscular Dystrophy (DMDC)

Researcher: Associate Prof. Peleg Hasson|Prof. Avi Schroeder

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Fibrosis, or scarring caused by the excessive deposition of extracellular matrix (ECM) is implicated in 45% of deaths in the western world. It is a key pathological feature of diseases like Duchenne Muscular Dystrophy (DMD) and multiple inflammatory and autoimmune...
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Categories: Pharmaceuticals and Biotechnology - OLD

Machine learning based single-molecule protein identification and quantification in nanochannels

Researcher: Prof. Amit Meller

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This single-molecule sensing technology enables high-resolution identification and quantification of intact proteins using ultra-thin silicon nanochannels. Unlike conventional methods that rely on protein fragmentation or antibody-based capture, this novel technology utilizes chemo-selective dual-color labeling and electrophoretic separation to produce protein-specific...
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Categories: Medical Devices - OLD|Pharmaceuticals and Biotechnology - OLD

Natural bioenhancer for improved bioavailability of lipophilic molecules

Researcher: Associate Prof. David Meiri

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Limited bioavailability remains a critical challenge in effectively delivering lipophilic active pharmaceutical ingredients (APIs), nutraceuticals, and food additives. Our novel technology addresses this challenge by utilizing pheophytin—a chlorophyll-derived compound—as a natural bioenhancer extracted from agricultural residues. Pheophytin significantly increases the...
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Categories: Pharmaceuticals and Biotechnology - OLD

Novel antibody-drug conjugate targeting immunotherapy-resistant tumors

Researcher: Prof. Yuval Shaked

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Immune checkpoint inhibitors (ICIs) have transformed cancer treatment by offering durable responses in a subset of patients with advanced malignancies. However, most patients either fail to respond or eventually develop resistance, creating an urgent need for strategies to overcome this...
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Categories: Pharmaceuticals and Biotechnology - OLD

Waveguide-enhanced nanopore system for single-molecule detection

Researcher: Prof. Amit Meller

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This waveguide-enhanced nanopore system enables solid-state, single-molecule detection with high sensitivity and optical precision. It integrates a metallic nanowell structure with a nanopore drilled into a silicon nitride membrane, combining optical waveguiding with ionic current sensing to achieve dual-mode detection....
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Categories: Medical Devices - OLD|Pharmaceuticals and Biotechnology - OLD
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