3D printed biodegradable implants
In severe nerve injuries, major gaps are formed within the tissue and the axons in the spinal cord fail to regenerate. This failure is related to the formation of cystic cavities within the injury site. Unlike healthy extra-cellular matrix, the...
Categories:
FoodTech & Biotechnology|Medical Devices & Digital Health
3D Printed Spacer Fabrics (3DSF)
Knitted Spacer Fabrics (SF, AKA spacer mesh) have numerous uses in the fashion, automobile, safety industries, and more. Nevertheless, current SFs manufacturing suffers from some substantial limitations. The knitting machines are huge and very expensive, and the process requires a...
Categories:
Automotive, Aerospace & Industry 4.0|Chemistry & Materials|Medical Devices & Digital Health
Microtia, which refers to a small and malformed external ear, occurs with an incidence of 1 to 10 per 10,000 births. Among surgical techniques of microtia repair, autologous reconstruction using costal cartilage is the most widely accepted. Autologous reconstruction using...
Categories:
Medical Devices & Digital Health
3D scaffolds of embedded olfactory ensheathing cells
Olfactory bulb (OB)-derived cells include fibroblasts, astrocytes, and olfactory ensheathing cells (OECs). OECs are a distinctive type of glia that secrete neurotrophic factors and form myelin sheaths around axons projecting from the olfactory mucosa into the OB of the central...
Categories:
FoodTech & Biotechnology|Medical Devices & Digital Health
A flap for de-novo tissue regeneration
Abdominal wall defects caused by severe trauma, burn or cancer ablation involve significant tissue loss (i.e.: the skin, subcutis, muscle and fascia layers), often requiring surgical reconstruction. Various techniques have been used in the final phase of management of abdominal wall...
Categories:
Chemistry & Materials|FoodTech & Biotechnology|Medical Devices & Digital Health
A miniature electron spin resonance probehead for transcutaneous oxygen monitoring
Oxygen concentration in the skin (denoted as transcutaneous oxygen - TcpO2) has a significant diagnostic and therapeutic importance in many clinical situations. It is being used for monitoring the condition and assessment of healing potential of chronic wounds, diabetic feet,...
Categories:
Chemistry & Materials|Electro-Optics & Quantum|Medical Devices & Digital Health
Adhesive composition reinforced with short fibers
Pancreatic surgery and specifically partial pancreaticoduodenectomy for malignant indication are generally accompanied by high complication and mortality rates. The poor results seen following the Whipple operation are mainly due to leakage from the pancreatoenteric anastomosis. Surgical sealants play a crucial...
Categories:
FoodTech & Biotechnology|Medical Devices & Digital Health
AI analysis for ECG telemedicine
Diagnosis of the cardiac condition involves the analysis of an ECG image through a visual examination of the printed physical output of the recording. The technology enables an automated analysis employing innovative deep-learning methods. The research, enables immediate analysis of...
Categories:
AI & Data Science|Medical Devices & Digital Health
AI-driven platform for diagnosis, risk prediction and management of cardiac conditions
Machine Learning (ML) driven cardiology platform that develops a cloud-based, ML-powered ECG analysis tools. It supports the diagnosis, risk prediction and management of cardiac conditions. The platform enables clinicians and technicians to perform ECG analysis faster and with better performance...
Categories:
Medical Devices & Digital Health
AI-enhanced low-field MRI reconstruction
Technology Magnetic Resonance Imaging (MRI) is one of the most important diagnostic tools in medicine, providing unparalleled visualization of internal anatomy and soft tissues without harmful radiation. Despite its strengths, MRI suffers from long acquisition times, which increase patient discomfort,...
Categories:
AI & Data Science|Medical Devices & Digital Health
AI-powered omics prediction from histology for enhanced diagnostics, response prediction and explainability
Technology This AI-driven technology predicts omics signatures directly from histological biopsy images, transforming standard pathology into a multi-omics-powered diagnostic tool. The method integrates machine learning to map molecular data onto histology, enabling precise prognosis and personalized treatment decisions. Tested on...
Categories:
AI & Data Science|Medical Devices & Digital Health|Therapeutics & Diagnostics
An ultra-sensitive nanopore biosensors for detection of KRAS mutations in colorectal cancer
One of the main challenges impeding genomic-based disease identification and characterization stems from the fact that related analytes, such as pathogens genes and cancer biomarkers, are present in extremely low concentrations in biomedical samples. Thus, currently, most clinical genomic identification approaches...
Categories:
Medical Devices & Digital Health|Therapeutics & Diagnostics
Aneurysm are blood filled saccular lesions located on bends and bifurcations of arteries. Cerebral aneurysms, for example, occur in about 5% of the population where 0.2% rupture with a mortality rate of nearly 50% . The available treatment can be...
Categories:
Medical Devices & Digital Health
Ankle-foot Orthosis with adjustable load bearing
Millions of individuals unable to bear weight on their foot or ankle due to conditions such as fractures, sprains, surgeries, and diabetic ulcers rely on crutches. However, crutches come with significant drawbacks: they are slow, energetically inefficient, functionally limiting, and...
Categories:
Medical Devices & Digital Health
Atrial fibrillation prediction
Prediction algorithm for Atrial Fibrillation risk based on novel algorithms that provide earlier more robust detection of AF risk and events based on ECG signal analysis. The technology is based on novel methods for analysis of HRV (Heart rate variability)...
Categories:
AI & Data Science|Medical Devices & Digital Health
Automated MRE-based analysis of Crohn’s disease extent
To date, ileocolonoscopy is the reference standard for evaluating disease activity in Crohn's disease (CD). However, this is an invasive procedure that is, generally, poorly tolerated by the patient and which only allows for the mucosal surface to be visualized...
Categories:
AI & Data Science|Medical Devices & Digital Health
Bio-convergent approach for predicting clozapine response in schizophrenia
Schizophrenia (SZ) is a severe, incurable chronic psychiatric disorder with a worldwide prevalence of about 1% and a peak onset in late adolescence or early adulthood. The disorder is characterized by disturbances in the main human capabilities - perception, emotion,...
Categories:
AI & Data Science|Medical Devices & Digital Health|Therapeutics & Diagnostics
Bio-inspired route for toughing ceramics
In contrast to synthetic materials, materials produced by organisms are formed in ambient conditions and with a limited selection of elements. Nevertheless, living organisms reveal elegant strategies for achieving specific functions, ranging from skeletal support to mastication, from sensors and...
Categories:
Chemistry & Materials|FoodTech & Biotechnology|Medical Devices & Digital Health
Biocompatible adhesive microneedle for tissue repair and sealing
Adhesion of soft tissues, as well as their sealing, are of great significance in the clinical and Medical fields. Closing wounds with tissue adhesives presents challenges, as well as a significant opportunity to revolutionize bleeding control and to heal....
Categories:
FoodTech & Biotechnology|Medical Devices & Digital Health
Biocompatible Tissue Adhesive Polymer
Tissue bioadhesives are widely used in dermatology, surgery rooms, and in the field. Despite their advantages over sutures and staples, currently available tissue glues are limited by their mechanical properties and toxicity. Here, a new approach is described for wound...
Categories:
Medical Devices & Digital Health
Biodegradable ureteral stent
Ureteral stents are widely used in urology, mainly to secure drainage of urine from the kidney to the bladder. Several weeks or months after insertion, these stents need to be removed by an in-office procedure. To avoid the unpleasant in-office...
Categories:
Medical Devices & Digital Health
The present technology provides a method for generating a fiber from a globular protein, such as albumin, by electrospinning. Thus, albumin fibers and fabrics may be produced and used for wound dressing or for in/ex vivo tissue generation. Advantages Albumin...
Categories:
FoodTech & Biotechnology|Medical Devices & Digital Health
Biological scaffold for would healing
Devices and methods for the on site fabrication and/or implantation of different support structures (e.g., scaffolds) and therapeutic agents (biological and or pharmaceuticals) for the healing of compromised tissues, whereby the scaffolds and therapeutic agents are each tailored to achieve...
Categories:
Chemistry & Materials|Medical Devices & Digital Health
Biomarker monitoring for early treatment
BiomarkerFlow is a diagnostic platform that enables rapid, multiplexed detection of biomarkers through advanced computational microscopy and microfluidics. It provides a breakthrough alternative to conventional immunoassays, such as ELISA and ECLIA, by offering faster, more scalable, and cost-effective analysis with...
Categories:
Electro-Optics & Quantum|FoodTech & Biotechnology|Medical Devices & Digital Health
Bone regeneration using a composite bone ECM graft
Bone defects resulting from trauma, infection, tumors or inherent genetic disorders pose a significant burden on healthcare systems. Bone regeneration requires the use of grafting materials such as bone autografts, which are currently considered the gold standard treatment. Nevertheless, their...
Categories:
FoodTech & Biotechnology|Medical Devices & Digital Health
Brain modulation for immune system regulation (specific to the reward system)
We show in mice that through activation or inhibition of the dopaminergic neurons in the Ventral Tegmental Area (VTA) in the brain we can alter the immune response. We can control the activity of distinct immune cell lineages, and in...
Categories:
Medical Devices & Digital Health|Therapeutics & Diagnostics
Cancer diagnostics of biopsies measured by spectral imaging
Cancer diagnosis from biopsies traditionally relies on manual microscopic examination by pathologists, a method prone to variability and errors due to increasing demand and shortage of trained personnel. This groundbreaking technology employs advanced spectral imaging combined with artificial intelligence (AI)...
Categories:
AI & Data Science|Medical Devices & Digital Health|Therapeutics & Diagnostics
Cancer immunotherapy by nanoparticle-based magnetic support in T cells
Cancer immunotherapy shows poor clinical results in many cancer types. A potent suppressor mechanism is the deprivation of required metabolic nutrients from T cells. Tumors compete with T cells for the same essential nutrients including glucose and amino acids, and...
Categories:
AI & Data Science|Medical Devices & Digital Health|Therapeutics & Diagnostics
Cell fusion or destruction using nanoparticles and laser
The present technology involves the use of nanoparticles and laser light to manipulate selected cells for cancer therapy, tissue regeneration and drug production. The invention describes a method for specific cell manipulation. Gold nanoparticles are coated by a layer of...
Categories:
Electro-Optics & Quantum|Medical Devices & Digital Health
Cell invasiveness is a major step in tumor metastasis therefore its evaluation is critical for prognosis of cancer progression and will affect treatment protocols. Currently, metastasis prognosis is based on subjective clinical judgment, patient characteristics, disease statistics, tumor shape/size, lymph-node...
Categories:
FoodTech & Biotechnology|Medical Devices & Digital Health|Therapeutics & Diagnostics
CMOS ISFET sensitive detector
Researcher:
Prof. Emeritus Yael Nemirovsky
Ion sensitive field effect transistors (ISFET), are used to detect presence and concentrations of various species of ions in fluids into which they are placed. ISFETs have long been considered good candidates for providing small, fast, sensitive, accurate, and relatively...
Categories:
Computer Science & Electrical Engineering|Medical Devices & Digital Health
Coded aperture ultrasound detector
Optoacoustic tomography (OAT) offers the unique capability to image optical contrast deep in the tissue. While OAT can produce very detailed images of blood vessels and lipid deposition, making it a potential solution to many clinical challenges, it requires 1000’s...
Categories:
Computer Science & Electrical Engineering|Electro-Optics & Quantum|Medical Devices & Digital Health
Computer vision respiratory rate detection
Detection of breathing patterns and abnormalities utilizing a video camera. Analysis of video monitoring of chest movement during breathing provides data regarding the beating pattern and enables rapid response to changes. Advantages Detection of apnea, bradypnea, eupnea and tachypnea No...
Categories:
AI & Data Science|Medical Devices & Digital Health
Deformation analysis of myocardium layers to identify damage to myocardium caused by chemotherapy in breast cancer patients
This breakthrough innovation helps doctors protect the hearts of women undergoing breast cancer treatment. Many breast cancer therapies, especially chemotherapy, can quietly damage heart muscle long before symptoms appear. This AI-powered echocardiography platform enables early detection of heart injury caused...
Categories:
Medical Devices & Digital Health
Detection of x-ray and gamma-ray photons
Detection of high energy photons (x-rays and gamma rays) is of great importance for applications in medical radiography, security inspection, radiation exposure monitoring, and high energy physics. Scintillation, which is the ability of certain materials to absorb high-energy (KeV scale)...
Categories:
Electro-Optics & Quantum|Medical Devices & Digital Health
Determining responders to inflammatory bowel disease treatment
Current treatment of Inflammatory bowel diseases (IBDs) is an empiric process, which involves decisions based on the response to therapies by the average patient, without taking into account the basic differences between patients, their specific immune status at a given...
Categories:
AI & Data Science|Medical Devices & Digital Health|Therapeutics & Diagnostics
Development extracellular arteries skeleton with a small diameter vascular tissue engineering
Heart failure is a key factor in morbidity and mortality in the western world. Heart muscle tissue differentiates shortly after birth, with the result that cardiac cells lose their ability to divide. As a result, the heart muscle tissue cannot...
Categories:
Medical Devices & Digital Health|Therapeutics & Diagnostics
Early detection of myocardial injury
Organ failure due to cardiovascular collapse is a leading cause of mortality in all the intensive cardiac units (ICUs). Myocardial injury is the most cardinal problem in this setting, and proper management of myocardial injury requires early detection. Missing the...
Categories:
AI & Data Science|Medical Devices & Digital Health|Therapeutics & Diagnostics
Electrospun-coated medical devices
Intubation-related morbidity is a well-known complication that usually involves the larynx and trachea. These problems are secondary to airway mucosal damage due to the presence of an endotracheal tube (ETT) which creates local pressure and pressure-like ulcer. The common clinical approach...
Categories:
Medical Devices & Digital Health
Elephant trunk (robotic mechanism with two degrees of freedom)
The present invention relates to the field of robotic actuated mechanisms, especially those having a high load lifting capability and light weight, such that they are capable of being stacked end-to-end to provide a hyper-redundant, high flexibility, long robotic arm....
Categories:
Automotive, Aerospace & Industry 4.0|Medical Devices & Digital Health
Explainable AI for COVID clasification in lung ultrasound images
Evaluation of Lung function is essential for the diagnosis and treatment of COVID patients. Ultrasound imaging is widely used and enables patient testing without moving the patient to an imaging facility. Determining patient treatment options and potential outcome in a...
Categories:
Medical Devices & Digital Health
Extracellular matrix-based cardiac scaffolds for cardiac tissue regeneration
Cardiovascular diseases and myocardial infarction (MI) in particular are the leading cause of death in the developed world. The only therapeutic options currently available for end-stage heart failure are mechanical ventricular assist devices or heart transplantation. However, these options have...
Categories:
FoodTech & Biotechnology|Medical Devices & Digital Health
Fibrin matrix for engineering tissue substitutes with internal blood vessel network
Tissue engineering holds enormous potential to replace or restore the function of damaged tissues. However, the most successful applications have been limited to thin avascular tissues such as skin and cartilage in which delivery of nutrients and oxygen relies on...
Categories:
FoodTech & Biotechnology|Medical Devices & Digital Health|Therapeutics & Diagnostics
Flow bioreactor device for monitoring cellular dynamics
Engineered 3D constructs have gained increased attention as in vitro tools for the study of cell–cell and cell–matrix interactions and are being explored for potential use as experimental models or therapeutic replacements of human tissues. Perfusion culture enhances oxygen and...
Categories:
FoodTech & Biotechnology|Medical Devices & Digital Health
Flow routing to inhibit thrombosis in replacement heart valves
Valvular heart disease affects more than 100 million people worldwide and is associated with significant morbidity and mortality. There are two common types of surgical prosthetic heart valves: Mechanical Heart Valve (MHV) or the Biologically-inspired and derived valve (BHV). Valve...
Categories:
Medical Devices & Digital Health
Flexible and Adaptable Ankle Foot Orthosis (FAAFO) device is a patented technology designed to correct the walking style and ankle joint rotation trajectory during the gait for patients with foot lifting (dorsiflexion) and foot rotation upward (evertion) disabilities. The device...
Categories:
Medical Devices & Digital Health
Free-breathing myocardial T1 mapping with physically-constrained motion correction
Technology Quantitative cardiac T1 mapping via MRI is crucial for diagnosing myocardial diseases such as fibrosis, inflammation, and hypertrophy. Traditional cardiac MRI requires patients to hold their breath, limiting accessibility for pediatric, elderly, and respiratory-compromised individuals. This innovative technology addresses...
Categories:
AI & Data Science|Medical Devices & Digital Health
Glaucoma diagnosis using a deep learning
Retinal imaging is widely available and enables affordable examination of the eyes. An optical coherence tomography (OCT) image, is a type of medical imaging technique that provides high-resolution, cross-sectional images of biological tissues, primarily in the eye. Digital fundus imaging...
Categories:
AI & Data Science|Medical Devices & Digital Health
Glucose and lactate continuous monitoring
A great effort has been made to establish efficient electron transfer between electrodes and enzymes. The protein shell of the enzyme prevents electrical communication with electrodes, therefore, redox mediators are required for activation. present new methodology to establish efficient electron...
Categories:
FoodTech & Biotechnology|Medical Devices & Digital Health|Therapeutics & Diagnostics
Harnessing synthetic optogenetic circuits for cancer therapy
Cancer immunotherapy is associated with on-target, off-tumor cytotoxicity or immune-related adverse events. Thus, light-based techniques, optogenetics, could allow “remote control” of immune responses within the body. Harnessing synthetic biology, optogenetics, the use of light to control the activity of specific...
Categories:
Medical Devices & Digital Health|Therapeutics & Diagnostics
Heart rate variability analysis in mammalians
The time variation between consecutive heartbeats is commonly referred to as heart rate variability (HRV). Loss of complexity in HRV has been documented in several cardiovascular diseases and has been associated with an increase in morbidity and mortality. However, the...
Categories:
AI & Data Science|Medical Devices & Digital Health
High-resolution immune-aging profiling and cardiovascular risk
Over the past decade it has become apparent that the aging immune system has a fundamental role in a variety of chronic illness, including cardiovascular disease, cancer, neurodegeneration, musculoskeletal conditions and others. This places the immune system as an “aging...
Categories:
AI & Data Science|Medical Devices & Digital Health|Therapeutics & Diagnostics
Hydrogel microparticles fabrication system
Hydrogel microparticles (HMPs) are composed of 3D crosslinked polymers on a microscopic scale. Due to their special material properties, they have become an important class of pharmaceutical formulations in the biotechnology and biomedical field. Current methods to produce HMPs such...
Categories:
Chemistry & Materials|FoodTech & Biotechnology|Medical Devices & Digital Health
Implementation of the brutal cardiovascular insights for monitoring and treating heart failure patients
Heart failure is a pandemic in the western world. Dyspnea is the most cardinal symptom of heart failure. Dyspnea is associated with poor quality of life and causes frequent rehospitalization. The main problem is optimization of treatment and prevention of...
Categories:
Medical Devices & Digital Health
In vitro model of heart failure with preserved ejection fraction (HFpEF)
Heart failure with preserved ejection fraction (HFpEF) is a non-infectious pandemic affecting more than 1% of the general population and more than 10% of individuals over the age of 65. Currently, there are no effective treatments for HFpEF, mainly due...
Categories:
Medical Devices & Digital Health|Therapeutics & Diagnostics
level of GSH early after stroke , as a biomarker for motor recovery
Stroke is one of the leading causes of disability globally, and often severely reduces quality of life by causing physical impairments that affect neuromuscular function. To date, treatment for stroke is limited, and often, interventions are improper with respect to...
Categories:
Medical Devices & Digital Health
Linear motion in a cylinder using helical wave generator in elastic component. A large static radial holding force is formed in addition to the linear motion created by the elliptical movement. The motion is precise and requires low power engine...
Categories:
Automotive, Aerospace & Industry 4.0|Medical Devices & Digital Health|Sustainability Energy & ConTech
Lirot.AI AI-driven analysis of ophthalmology images
Technology Autonomous AI-Driven Retinal Disease Screening Platform for Primary Care Executive Summary Lumière.ai is a fully autonomous advanced AI-powered screening platform designed to detect major sight threatening retinal diseases including glaucoma, diabetic retinopathy (DR), age-related macular degeneration (AMD), and retinal...
Categories:
AI & Data Science|Medical Devices & Digital Health
MELoDee - multi-exponential model learning based on deep neural networks
The present technology offers a machine-learning solution to the problem of fitting multi-exponential models to observed data. The multi-exponential fitting problem appears in various science and engineering applications, such as nuclear magnetic resonance spectroscopy, lattice quantum chromodynamics, pharmaceutics and chemical...
Categories:
AI & Data Science|Medical Devices & Digital Health
Metabolic biomarker platform for predicting immunotherapy outcomes
Immunotherapy has revolutionized cancer treatment, but patient response remains unpredictable, with success rates varying significantly across different cancer types. This technology introduces a metabolic biomarker platform derived from single-cell RNA sequencing of tumor-infiltrating immune cells. By analyzing over one million...
Categories:
AI & Data Science|Medical Devices & Digital Health|Therapeutics & Diagnostics
Methacrylated fibrinogen hydrogel precursors
Technology Hydrogel biomaterials that are biodegradable are often sought in the field of regenerative medicine and 3D bioprinting. Biomedical hydrogels comprised of natural polymers such as chitosan, alginate, gelatin, albumin, fibrin and collagen have gained interest for their inherent biocompatibility...
Categories:
FoodTech & Biotechnology|Medical Devices & Digital Health|Therapeutics & Diagnostics
Microfluidic device that is designed to mimic the geometry of a section of the pulmonary acinus
Assessing deposition levels of air-borne particulate matter in the pulmonary acinus is of utmost importance for the pharmaceutical industry where such knowledge is required for development and quality validation of inhaled aerosolized drugs. In addition, deposition levels of toxic particles...
Categories:
Chemistry & Materials|Medical Devices & Digital Health|Therapeutics & Diagnostics
Miniature surgical robot for knee arthroplasty
Arthritis is an increasing global problem with 10% of men and 18% of women having symptomatic osteoarthritis by the age of sixty. Consequently, the number of hip and knee replacements has increased rapidly in most OECD countries by 35% and...
Categories:
Medical Devices & Digital Health
Miniaturized Ultrasound Detectors
Ultrasound technology today is bulky and involves imaging probes with typical sizes of several centimeters. We have developed a new methodology for ultrasound imaging that can achieve extreme levels of miniaturization preserving high-resolution. This platform relies on optical technology for...
Categories:
Computer Science & Electrical Engineering|Electro-Optics & Quantum|Medical Devices & Digital Health
Mold-less molding additive manufacturing of volumetric objects
Traditional additive manufacturing methods such as 3D / 4D printing, Selective laser sintering (SLS), Stereolithography (SLA), Digital light process (DLP) and Volumetric additive manufacturing (VAM) are powerful tools for prototyping, but they’re limited by slow build speed and inhomogeneous mechanical...
Categories:
Automotive, Aerospace & Industry 4.0|Chemistry & Materials|Medical Devices & Digital Health|Sustainability Energy & ConTech
Molecular profiling of cancer by analysis of tissue histomorphology
Deep learning-based method for mapping critical receptors on cancer cells. Using digital images of biopsies taken from breast cancer patients, the new technology is expected to significantly improve personalized cancer treatments. The technology extracts molecular information from biopsy images that...
Categories:
AI & Data Science|Medical Devices & Digital Health
Neural inhibition for treating bowel diseases
Researcher:
Prof. Asya Rolls
Inflammatory Bowel Disease (IBD) is a group of complex inflammatory disorders involving the gastrointestinal tract. It is a chronic condition with no medical cure, which commonly requires a lifetime of care. To this day, the mechanism of the disease's pathophysiology is...
Categories:
Medical Devices & Digital Health|Therapeutics & Diagnostics
Neurofeedback and induction of an immune response
Researcher:
Prof. Asya Rolls
Recently, a causal link between activation of the reward system and an immune function was reported in mice. This discovery holds great potential for improving personal health management, rationalizing the use of reward-related brain activation to enhance immune function. The...
Categories:
Medical Devices & Digital Health|Therapeutics & Diagnostics
Neuronal modulation to control the immune response
Researcher:
Prof. Asya Rolls
We show in mice that through activation or inhibition of the dopaminergic neurons in the Ventral Tegmental Area (VTA) in the brain we can alter the immune response. We can control the activity of distinct immune cell lineages, and in...
Categories:
Medical Devices & Digital Health|Therapeutics & Diagnostics
Non-invasive imaging of metabolites by MRI
The new technology developed at the Technion can hyperpolarize metabolites with stables radicals created in their solid form, without the need to co-dissolve them with potentially toxic exogenous radicals, Magnetic Resonance Imaging (MRI) is the most informative of all medical...
Categories:
Chemistry & Materials|Medical Devices & Digital Health
Pacemaker signature in the ECG signal
Multiple Heart Rate variation analysis methods based on ECG and/or other signals are deployed in an algorithm which analyses SA node function in order to provide early warning for pacemaker issues. The technology enables early detection of Heart pacemaker issues...
Categories:
AI & Data Science|Medical Devices & Digital Health
Personalized clinical decision support for heart failure patients
Technology Heart failure remains a leading cause of mortality, with 20% of patients dying within one year of diagnosis and 50% within five years. Current treatment approaches are often generalized and fail to account for the complex interplay between heart...
Categories:
AI & Data Science|Medical Devices & Digital Health|Therapeutics & Diagnostics
Plant proteins as edible matrixes
Cultivated meat is considered one of the leading solutions to the global food crisis, offering conventional meat-like nutritional values and eating experiences without harming animals and with a much lower environmental footprint compared to conventional meat production. The development of...
Categories:
FoodTech & Biotechnology|Medical Devices & Digital Health
Polymers to trap uremic toxins in WAK (Wearable artificial kidney)
Renal failure is a medical condition in which the kidneys fail to function adequately. The treatment given to patients suffering from renal failure are dialysis or kidney transplant. Different studies done in recent years, indicate that frequent and prolonged dialysis...
Categories:
Chemistry & Materials|Medical Devices & Digital Health
Protein-based polymers as the active layer in electronic devices
Using sustainable and affordable proteins as the basis for the formation of a new family of environmental polymers that are free-standing, soft, elastic, and most importantly, their electronic and ionic conductivity can be engineered. A special focus is given to...
Categories:
Chemistry & Materials|Medical Devices & Digital Health|Sustainability Energy & ConTech
Proteomics and genomics applications for electrokinetic focusing of in single-molecule sensor
The present patented technology is in the field of single-molecule detection in cases where the source sample is extremely dilute to the point where measurement is prohibited. Single molecule nanopore biosensors are integrated down-stream of a fluidic device that features...
Categories:
Medical Devices & Digital Health|Therapeutics & Diagnostics
Proteomics in single-molecule sensor
The present patented technology is in the field of single-molecule detection in cases where the source sample is extremely dilute to the point where measurement is prohibited. Single molecule nanopore biosensors are integrated down-stream of a fluidic device that features...
Categories:
Medical Devices & Digital Health|Therapeutics & Diagnostics
Radar-based imaging system for non-invasive tracking of gold nanoparticles
This technology introduces a non-invasive deep-tissue imaging system that uses millimeter-wave (mmWave) radar to detect and track gold nanoparticles (GNPs) in biological tissues. The system transmits low-power, non-ionizing radar signals and analyzes their reflections to localize and monitor the spatial...
Categories:
Medical Devices & Digital Health|Therapeutics & Diagnostics
Rapid clinical antimicrobial susceptibility diagnostic system
Technology By the year 2050, antimicrobial resistance is predicted to cost the world over 100 trillion US$ cumulatively and claim 10 million lives per year. Thus, there is an urgent need to develop diagnostic methods that will help physicians to...
Categories:
FoodTech & Biotechnology|Medical Devices & Digital Health|Therapeutics & Diagnostics
Real time mitochondrial dimension measurements
Mitochondrial volume is correlated with cell function and internal cell processes. Changes in mitochondrial volume were associated with advanced states of cardiac disease. Thus, measurements of mitochondrial dimension deformations are important to the understanding of cell function and its deterioration....
Categories:
AI & Data Science|Medical Devices & Digital Health
A robotic biomechanical shoe, which provides real-time feedback regarding forces acting on the foot of the user, in order to modify these forces in a corrective or diagnostic manner. The shoe comprises an insole (that can function independently) equipped with...
Categories:
Medical Devices & Digital Health
The self-contained operating table serves as a central integrated unit, replacing the radial layout that disperses cables and tubes in and outward. By consolidating equipment beneath and around the table, this compact design minimizes clutter (spaghetti effect), enhances safety, enable...
Categories:
Medical Devices & Digital Health
Self-correcting non-invasive brain computer interfaces
Non-invasive Brain Computer Interfaces (BCIs) measure electroencephalography (EEG) potentials from the scalp and interpret them, through signal processing and machine learning, to make decisions and operate computers or other external devices. However, practical applications of BCIs are hampered due to...
Categories:
Computer Science & Electrical Engineering|Medical Devices & Digital Health
Self-healing multifunctional wound dressing
Traditional wound closure methods, including sutures, staples, and medical adhesives, have been widely used in the medical field. However, these methods often lead to complications due to mechanical mismatches with the skin's natural properties. These complications may include infection, damage...
Categories:
Chemistry & Materials|Medical Devices & Digital Health|Therapeutics & Diagnostics
Self-sterilized polymers for coatings and printing
Researcher:
Prof. Yoav Eichen
Low migration, low odor UV curable polymer compositions designed to passively self-sterilize in an accelerated process, without any need for human intervention The polymers are amenable to coating, 2D- as well as 3D-printing Irreversible immobilization onto the surface and accelerated...
Categories:
Automotive, Aerospace & Industry 4.0|Chemistry & Materials|FoodTech & Biotechnology|Medical Devices & Digital Health
Sensitive sensors for new nanoparticle resonance biomedical applications
Optical interrogation of targets enables a non-destructive way by which to extract useful information on critical target parameters. Such methods predominantly employ either angular or spectral interrogation, in which the target is illuminated at different incidence angles or wavelengths, respectively....
Categories:
Chemistry & Materials|Electro-Optics & Quantum|Medical Devices & Digital Health
Separation and concentration of oxygen
Separation of oxygen from ambient air is currently done using cryogenic and sorption processes. Although the present technology is very common and currently most of the oxygen is being produced using these methods, cryogenic and sorption processes are high energy...
Categories:
Chemistry & Materials|FoodTech & Biotechnology|Medical Devices & Digital Health
Spectrally encoded imaging of tympanic membrane vibrations
According to the World Health Organization, over 5% (466 million) of the global population suffer from some sort of disabling hearing loss [1]. The annual cost of unaddressed hearing problems is estimated to be above $750 billion, mainly due to...
Categories:
Electro-Optics & Quantum|Medical Devices & Digital Health
Sperm-induced cell-to-cell fusion as a male fertility diagnosis test
Approximately 15% of couples of reproductive age face fertility issues, with about a third attributed to male factors. Assisted Reproductive Techniques (ART), such as the conventional in vitro fertilization (IVF), and intracytoplasmic sperm injection (ICSI), are commonly employed to aid...
Categories:
Medical Devices & Digital Health|Therapeutics & Diagnostics
Stable broad-spectrum decoy antivirals
This broad-spectrum antiviral nanoparticle technology leverages artificial intelligence (AI) and synthetic biology to develop decoy receptors that neutralize viruses before they infect human cells. These nanoparticles are composed of synthetic long non-coding RNA (slncRNA) molecules, which self-assemble with virus-targeting receptor...
Categories:
Medical Devices & Digital Health|Therapeutics & Diagnostics
Super-resolution optical microscopy utilizing structured illumination
Standard optical microscopy has a resolution limit of roughly 200nm which is insufficient for modern Biological research. Research of intra-cellular structures requires sub 50nm resolution for dynamic in-vivo studies. Current methods to achieve such resolution are slow or destructive. Illuminating...
Categories:
Chemistry & Materials|Electro-Optics & Quantum|FoodTech & Biotechnology|Medical Devices & Digital Health
System and method for electron spin resonance
This technology addresses a significant limitation in traditional MRI, which is excellent in damaging anatomical structures, but can say very little as to their physiological condition. An anatomical structure can be hypoxic, enflamed, even dead, yet none of that would...
Categories:
Chemistry & Materials|Electro-Optics & Quantum|Medical Devices & Digital Health
Systems and methods for ultrasonic imaging
Medical ultrasound is a wide-spread imaging modality due to its high temporal resolution, lack of harmful radiation and cost-effectiveness, which distinguishes it from other modalities such as MRI and CT. High temporal resolution is highly desired in additional to spatial...
Categories:
Computer Science & Electrical Engineering|Medical Devices & Digital Health
Targeted delivery of inhalation medicine using magnetic particles
The lungs can be described as a dense tree, where the airways resemble branches, ending with raspberry-like acinar sacs. The acinar sacs are made of alveoli, the basic respiratory units of the lungs. The alveolar lumen is composed of a...
Categories:
Medical Devices & Digital Health|Therapeutics & Diagnostics
TERA Hz radiation transmitter
The terahertz region of the electromagnetic spectrum, in particular the region of 1-10 THz, is called the “terahertz gap” due to the lack of convenient radiation sources which are either inefficient or require cooling and are not tunable in frequency....
Categories:
Electro-Optics & Quantum|Medical Devices & Digital Health|Security & Defence
Fungal infections are a significant and growing public health problem. Currently, there are two main pharmacological anti-fungal treatments approved by the US Food and Drug Administration (FDA): (1) Amphotericin B. This drug is considered the "gold standard" of antifungal therapy....
Categories:
Chemistry & Materials|Medical Devices & Digital Health
Ultrafast microscopy and spectroscopy
Time-resolved Imaging by Multiplexed Ptychography (TIMP) represents a significant breakthrough in ultrahigh-speed imaging, enabling the capture of dynamic, non-repetitive, ultrafast events. Unlike conventional ptychography, which is limited by slow scanning, or other high-speed imaging methods that often compromise resolution or...
Categories:
Electro-Optics & Quantum|Medical Devices & Digital Health
Ultrasensitive RNA and mRNA quantification using nanopores as biosensors
The ability to sense and digitally count individual RNA and mRNA biomarkers holds a great potential for early diagnosis of a wide range of diseases from cancer to infectious diseases, including the recent SARS-CoV-2. The ‘gold-standard’ method for RNA molecules...
Categories:
Medical Devices & Digital Health|Therapeutics & Diagnostics
Wearable multimodality haptic feedback device
Virtual and Augmented Reality (VR and AR) are rapidly evolving fields, with applications in multiple domains, from gaming to medicine. While the visual and auditory feedback provided have progressed greatly, accompanying devices for haptic feedback are still limited in their...
Categories:
AI & Data Science|Medical Devices & Digital Health
Wearable stretchable microneedles-based platform
Microneedles devices to monitor materials in the interstitial fluid or inject materials to it are widely used for a range of medical conditions. Those are hollow microneedles as they need to pass fluids from and to the body. As such...
Categories:
Chemistry & Materials|Medical Devices & Digital Health|Therapeutics & Diagnostics
X-ray free imaging for adolescent scoliosis diagnosis
Adolescent Idiopathic Scoliosis (AIS) is a prevalent disease that currently requires radiographic imaging for accurate diagnosis and treatment planning. Much work has been done to identify and classify scoliosis using surface and topographic measurements, but current techniques rely on local...
Categories:
AI & Data Science|Medical Devices & Digital Health|Therapeutics & Diagnostics
X-ray radiation source system
High quality energy tunable X-ray sources are important for many applications in various fields of research such as medical diagnostics, material treatment and analysis, food security and many others. Current state-of the-art sources as synchrotron radiation and free-electron laser (FEL)...
Categories:
Electro-Optics & Quantum|Medical Devices & Digital Health
